桂芎生物

BMLF1 protein (259-267) HLA-A*02:01

靶点说明

EBV是一种γ疱疹病毒，可以在宿主细胞内建立非生产性（潜伏）和生产性（裂解）感染。BMLF1 protein促进早期和晚期病毒mRNA的核输出。BMLF1 protein (259-267) GLCTLVAML 具有激活来自EBV阳性患者血液“记忆”病毒特异性CD8(+) T细胞的能力。

BMLF1 protein (259-267) 特异性T细胞存在于EBV携带人群中，直接控制病毒复制损伤。

在测量BMLF1 protein (259-267) 特异性CD8 + T细胞频率方面，BMLF1 protein (259-267) HLA-A*02:01四聚体染色获得的价值平均比从ELISOPOT高4.4倍，四聚体染色可从EBV病毒携带者PBMC中检出多达5.5％抗原特异性CD8 + T细胞。

HLA类型

HLA-A*02:01， 中国人分布频率12.036%

抗原和HLA的亲和力

NetMHCpan 4.1  计算GLCTLVAML与HLA-A*02:01亲和力为62.23nM，肽与HLA稳定结合。

产品类型和应用

产品类型规格价格
流式检测与分选BMLF1 protein (259-267) HLA-A*02:01 PE / APC / Alexa Fluor 4887200元/50ug, 11800元/100ug
磁珠分选BMLF1 protein (259-267) HLA-A*02:01磁珠8200元/50ug, 12800元/100ug
生物素化复合物BMLF1 protein (259-267) HLA-A*02:01-biotin6800元/50ug, 11400元/100ug

实测结果

肽刺激PBMC后检测抗原特异性CD8+T细胞

GLCTLVAML多肽刺激HLA-A*02:01限制性PBMC后，使用BMLF1 protein (259-267) HLA-A*02:01 PE 四聚体和抗CD8-FITC抗体检测。以未加抗原肽的细胞培养组为对照。

靶点结合的TCR序列

数据来源：IEDB数据库

T Cell Receptors – Group IDT Cell Receptors – SpeciesT Cell Receptors – Chain 1 CDR3T Cell Receptors – Chain 2 CDR3
257Homo sapiens (human)AEDNNARLMSARDGTGNGYT
20255Homo sapiens (human)CAADSNARFMFCSARDRVGNTIYF
20256Homo sapiens (human)CAADSNARLMFCSARDRVGNTIYF
20257Homo sapiens (human)CAAGYSSASKIIFCASSFSSGTTDTQYF
20258Homo sapiens (human)CAARFDSGYALNFCASSTYSGQSYGYTF
20259Homo sapiens (human)CAARFDSGYALNFCASSTYYGQSYGYTF
20260Homo sapiens (human)CAARGDTGKLIFCASSISGDYGYTF
20261Homo sapiens (human)CAASDGAGGTSYGKLTFCASSLWTGSHEQYF
20262Homo sapiens (human)CAASRDYKLSFCSVGAIMDEQFF
20263Homo sapiens (human)CADDNNARLMFCSARDRTGNGYTF
20264Homo sapiens (human)CAEDAGNMLTFCASSQAGLAAYNEQFF
20265Homo sapiens (human)CAEDAGNMLTFCSVTGDRRSNQPQHF
20266Homo sapiens (human)CAEDANARLMFCSARDGTGNGYTF
20267Homo sapiens (human)CAEDDNARLMFCSARDRVGNGHTF
20268Homo sapiens (human)CAEDDNARLMFCSARDRVGNGYTF
20269Homo sapiens (human)CAEDNNARLMFCSARDRTGNGYTF
20270Homo sapiens (human)CAEDNNARLMFCSARDGTGNGYTF
20271Homo sapiens (human)CAEDNNARLMFCASSPGSTAPGELFF
20272Homo sapiens (human)CAEDNNARLMFCSARDATGNGYTF
20273Homo sapiens (human)CAEDNNARLMFCSARDQTGNGYTF
20274Homo sapiens (human)CAEDNNARLMFCSARDSTGNGYTF
20275Homo sapiens (human)CAEDNNARLMFCSARDTTGNGYTF
20276Homo sapiens (human)CAEDNNARLMFCSARDTVGNGYTF
20277Homo sapiens (human)CAEDNNARLMFCSARLRELSGNTIYF
20278Homo sapiens (human)CAEDNNARLMFCSARLRKLSGNTIYF
20279Homo sapiens (human)CAEDNNARLMFCSARVEPGNGYTF
20280Homo sapiens (human)CAEDNNARLMFCSVGSGGTNEKLFF
20281Homo sapiens (human)CAEDNNPRLMFCSARDSTGNGYTF
20282Homo sapiens (human)CAEDNNTRLMFCSARDSTGNGYTF
20283Homo sapiens (human)CAEDNYGQNFVFCSGREDSTNEKLFF
20284Homo sapiens (human)CAEIASGTYKYIFCSAEISGTQLYNEQFF
20285Homo sapiens (human)CAEKGGTALIFCSARGQGDEQYF
20286Homo sapiens (human)CAEKGGTALIFCSERGQGDEQYF
20287Homo sapiens (human)CAELGNDMRFCASSQAPGGEQYF
20288Homo sapiens (human)CAELGNDMRFCASSQCPGGEQYF
20289Homo sapiens (human)CAELGNDMRFCASSQSPGGEQYF
20290Homo sapiens (human)CAENRCSTLTFCASSVAGGDEQFF
20291Homo sapiens (human)CAENRYSTLTFCASSVAGGDEQFF
20292Homo sapiens (human)CAESIGKLIFCSVGSGGTNEKLFF
20293Homo sapiens (human)CAESIGKLIFCSVGAGGTNEKLFF
20294Homo sapiens (human)CAESIGKLIFCSVGTQGTNEKLFF
20295Homo sapiens (human)CAESISGGKLIFCSVGSAGTNEKLFF
20296Homo sapiens (human)CAESKGNLIFCASSQSPGGEQYF
20297Homo sapiens (human)CAESLDMLTFCASSVVGGNEQFF
20298Homo sapiens (human)CAESNADNNDMRFCSVEAVGDGIYNEQFF
20299Homo sapiens (human)CAESQGNLIFCASSQRPGGQQFF
20300Homo sapiens (human)CAESQGNLIFCASSQSPGGQQFF
20301Homo sapiens (human)CAESSRGKLIFCSVGTGGTNEKLFF
20302Homo sapiens (human)CAESTCWGKLQFCSVGAGGTNEKLFF
20303Homo sapiens (human)CAESTGKLIFCSVGTGGTNEKLFF
20304Homo sapiens (human)CAESTGKLIFCSVGSDGTNEKLFF
20305Homo sapiens (human)CAESTSRGNTPLVFCASSLTTEQQFF
20306Homo sapiens (human)CAESTSWGKLQFCSVGAGGTNEKLFF
20307Homo sapiens (human)CAEYSSAFKIIFCASSQSPGGTQYF
20308Homo sapiens (human)CAEYSSASKIIFCASSQSPGGTQYF
20309Homo sapiens (human)CAHDNNARLMFCSARDRTGNGYTF
20310Homo sapiens (human)CAHDNNARLMFCSARDGTGNGYTF
20311Homo sapiens (human)CALNPTGGGNKLTFCASSPVSGSSYEQYF
20312Homo sapiens (human)CALPMNRDDKIIFCASSYAYDGSYEQYF
20313Homo sapiens (human)CALRCFGNEKLTFCSVPGTVQETQYF
20314Homo sapiens (human)CALRCFGNEKLTFCSVPITVQETQYF
20315Homo sapiens (human)CALRCFGNEKLTFCSVPSTVQETQYF
20561Homo sapiens (human)CAMREVMDSNYQLIWCASSVAQLAGGTDTQYF
20562Homo sapiens (human)CASDNNARLMFCSARDSTGNGYTF
20563Homo sapiens (human)CASGGSQGNLIFCASSFGTFETQYF
20564Homo sapiens (human)CASGGSQGNLIFCASSIGTFETQYF
20565Homo sapiens (human)CAVDDLYSNYQLIWCASSLSGGINEQFF
20566Homo sapiens (human)CAVDDLYSNYQLIWCASSLWGGINEQFF
20567Homo sapiens (human)CAVDDTGGGNKLTFCASSAGQVSPGELFF
20568Homo sapiens (human)CAVGEDSSYKLIFCSAEPETSGGLQYF
20569Homo sapiens (human)CAVGEDSSYKLIFCSAEPGTSGGLQYF
20570Homo sapiens (human)CAVLRGGADGLTFCASSSGAGLDEQFF
20571Homo sapiens (human)CAVNIDNMDSNYQLIWCASSVGGEAYEQYF
20572Homo sapiens (human)CAVNIDTMDSNYQLIWCASSVGGEAYEQYF
20573Homo sapiens (human)CAVPAEGGYNKLIFCSARDSTGNGYTF
20574Homo sapiens (human)CAVPPEGGYNKLIFCSARDSTGNGYTF
20575Homo sapiens (human)CAVPVEGGYNKLIFCSARDSTGNGYTF
20576Homo sapiens (human)CAVRCFGNEKLTFCSVPITVQETQYF
20577Homo sapiens (human)CAVRCFGNEKLTFCSVPSTVQETQYF
20578Homo sapiens (human)CAVRCFGNEKLTFCSVPIAVQETQYF
20579Homo sapiens (human)CAVYSNSGYALNFCSVGTGGTNEKLFF
20580Homo sapiens (human)CAVYSNSGYALNFCASSPDREGGDRGYNEQFF
20581Homo sapiens (human)CILGMDSSYKLIFCSVPGLAVPGELFF
20582Homo sapiens (human)CSHDNNARLMFCSARDRTGNGYTF
20583Homo sapiens (human)CSVNIDTMDSNYQLIWCASSVGGEAYEQYF
20584Homo sapiens (human)CVVFKAAGNKLTFCASGGSSYQETQYF
20585Homo sapiens (human)CVVNGMDSSYKLIFCASTPGTVLPDTQYF
20586Homo sapiens (human)CVVSDEYGNKLVFCASSVWTGHDEQFF
20587Homo sapiens (human)CVVYMEYGNKLVFCASGGLSSYNEQFF
20833Homo sapiens (human)CAMREQEDSNYQLIWCASSEESYLMNTEAFF
20834Homo sapiens (human)CIVSRTRRGNKLVFCASSQSPGGTQYF
20835Homo sapiens (human)CATSPPLTQGGSEKLVFCASSQSPGGTQYF
20836Homo sapiens (human)CAVEHNTDKLIFCASSQSPGGTQYF
20837Homo sapiens (human)CALSLSGYSTLTFCASSQSPGGTQYF
20838Homo sapiens (human)CAMSSAGGTSYGKLTFCASSQSPGGTQYF
20839Homo sapiens (human)CAVIYGNQFYFCASSLWVGGSSGANVLTF
20840Homo sapiens (human)CALYNTDKLIFCASSPTSGSVYEQYF
26849Homo sapiens (human)CAEDNNARLMFCSARDSTGNGYTF
26850Homo sapiens (human)CVVNGMDSSYKLXFCASSRGTVAPGELFF
27431Homo sapiens (human)CALYSNSGYALNFCASRPDSDYGYTF
27432Homo sapiens (human)CADPIEDAGNMLTFCASSDGQLTAGELFF
27433Homo sapiens (human)CAVGASRDYKLSFCASSFSSGTTDTQYF
27434Homo sapiens (human)CAYGGSQGNLIFCASSQGDVAPGTQYF
27435Homo sapiens (human)CADGSGTTDSWGKLQFCASSQNQDMGTEAFF
27436Homo sapiens (human)CAELGQKLLFCASSQSPGGTQYF
27437Homo sapiens (human)CAATDNTDKLIFCASSRLGDYTF
27438Homo sapiens (human)CAEDNNARLMFCSARIGVGNTIYF
27439Homo sapiens (human)CAEDNNARLMFCSARVGVGNTIYF
27440Homo sapiens (human)CAEDKDARLMFCSARDRIGNTIYF
27441Homo sapiens (human)CALDSTYSSASKIIFCSARDRTGNGYTF
27442Homo sapiens (human)CAEDSNARLMFCSARSGVGNTIYF
27443Homo sapiens (human)CAEDFNARLMFCSARTGVGNTIYF
27444Homo sapiens (human)CAEDQNARLMFCSARWGVGNTIYF
27445Homo sapiens (human)CAEVSGTYKYIFCSAWDREVVGTEAFF
35532Homo sapiens (human)CVVNTPNDYKLTFCASSEAGTSYYNEQFF
35533Homo sapiens (human)RVVNTPGNDKFTFCASSEAGTSYYNEQFF
35534Homo sapiens (human)CARKGNNGYKLVFCASSEGQIAPGELFF
35535Homo sapiens (human)CVVNGEDSSYKLIFCASSEGQIAPGELFF
35536Homo sapiens (human)SAMSGYTDYKLSFCASSEGQIAPGELFF
35537Homo sapiens (human)CGTEILNDYKLSFCASSEGQLSSGNTIYF
35538Homo sapiens (human)CVVNRPNDYKLSFCASSESAWVAGGSDTQYF
35539Homo sapiens (human)CVVNMEGYSTLTFCASSESPMWDPRYGYTF
35540Homo sapiens (human)CAISNFGNEKLTFCASSFTSGSIYEQYF
35541Homo sapiens (human)CAEDNNARLMFCASSGARDTQYF
35542Homo sapiens (human)CAEDNNARLMFCSARDQIGNGYTF
35543Homo sapiens (human)CAEDNNARLMFCSARDRTGNGYTF
35544Homo sapiens (human)CAMGGSNDYKLSFCASSGNPQTGPMNTEAFF
35545Homo sapiens (human)CLVVNDYKLSFCASSLAFSGLLTDTQYF
35546Homo sapiens (human)GTGTDDYKLSFCASSPGLVSSGELFF
35547Homo sapiens (human)CAVTGGAANKLIFCASSPGTSGYYNEQFF
35548Homo sapiens (human)CAFYNTDKLIFCASSPTSGSIYEQFF
35549Homo sapiens (human)CALYNTDKLIFCASSPTSGSIYEQFF
35550Homo sapiens (human)CALYNTDKLIFCASSPTSGSIYEQYF
35551Homo sapiens (human)CALYNTDKLIFCASSPTSGSVYEQFF
35552Homo sapiens (human)CALYNTDKLIVCASSPTSGSIYEQYF
35553Homo sapiens (human)CASYGTDKLIFCASSPTSGSIYEQYF
35554Homo sapiens (human)CAVRDGGNFNKFYFCASSPTSGSIYEQYF
35555Homo sapiens (human)CAGYNTDKLIFCASSPTSGSVYEQFF
35556Homo sapiens (human)CALFNTDKLIFCASSPTSGSVYEQFF
35557Homo sapiens (human)CAFTNTGNQFYFCASSPTSGSVYEQYF
35558Homo sapiens (human)VYVSDKDSTDKLIFCASSPTSGSVYEQYF
35559Homo sapiens (human)CAASQIGNEKLTFCASSPWDRGATNEKLFF
35560Homo sapiens (human)CADRQSQKDTFCASSQSPGGTQYF
35561Homo sapiens (human)CAELGYQKVTFCASSQSPGGTQYF
35562Homo sapiens (human)CAESTSASKIIFCASSQSPGGTQYF
35563Homo sapiens (human)CAVYSSASKIIFCASSQSPGGTQYF
35564Homo sapiens (human)CGTEIPHDYKLSFCASSTGQLSSGNTIYF
35565Homo sapiens (human)CAVNPDSSYKLIFCASSTGQVATNEKLFF
35566Homo sapiens (human)CAETVDKLIFCASSVVGNEQFF
35567Homo sapiens (human)CAEAMAGNMLTFCATSITSGSQTQYF
35568Homo sapiens (human)CAEDLNARLMFCAVGTESTNEKLFF
35569Homo sapiens (human)CASYGTDKLIFCCRSPRLARRRIYEQYF
35570Homo sapiens (human)CAVSTSYGKLTFCSAPRAGGGQETQYF
35571Homo sapiens (human)CAVDNNARLMFCSARDETGNGYTF
35572Homo sapiens (human)CAEDNNARLMFCSARDGTGNGYTF
35573Homo sapiens (human)CAEDRMPEIMFCSARDGTGNGYTF
35574Homo sapiens (human)CAEDADSTLTFCSARDGTGNTIYF
35575Homo sapiens (human)CAFDNNARLMFCSARDGVGNGYTF
35576Homo sapiens (human)CAEDNNARLMFCSARDQTGNGYTF
35577Homo sapiens (human)CAEDLNARLMFCSARDRIGNTIYF
35578Homo sapiens (human)CALYNTDKLIFCSARDRTGNGYTF
35579Homo sapiens (human)CVVNVPNDYKLSFCSARDRTGNGYTF
35580Homo sapiens (human)CAEDKNARLMFCSARDRVGNTIYF
35581Homo sapiens (human)CAEDYNARLMFCSARDRVGNTIYF
35582Homo sapiens (human)CAELDVQKLVSCSARDRVGNTIYF
35583Homo sapiens (human)CARNGYNDYKLSFCSARDRVGNTIYF
35584Homo sapiens (human)CAWQGNYGQNFVFCSARDRVGNTIYF
35585Homo sapiens (human)CAEDRYSTLTFCSARDSTGNGYTF
35586Homo sapiens (human)CAEDENARLMFCSARDVPGNTIYF
35587Homo sapiens (human)CAEDLNARLMFCSARFRENSGNTIYF
35588Homo sapiens (human)CAEDRDSTLTFCSARVGAGNTIYF
35589Homo sapiens (human)CAESGRGKLIFCSVGAGGTNEKLFF
35590Homo sapiens (human)CAEHAGQGNLIFCSVGGQANTEAFF
35591Homo sapiens (human)CAESTADGLTFCSVGGSFYGYTF
35592Homo sapiens (human)CPGDINARLMFCSVGGSFYGYTF
35593Homo sapiens (human)CAESIGGMRFCSVGQGGTNEKLFF
35594Homo sapiens (human)CAESPFSGNTPLVFCSVGSGGTNEKLFF
35595Homo sapiens (human)CAESPFSGNTPLVFCSVGTGGTNEKLFF
35596Homo sapiens (human)CAESISGGKLIFCSVGSQGINEKLFF
35597Homo sapiens (human)CAESISGGKLIFCSVGSQGTNEKLFF
35598Homo sapiens (human)CVVCRMDSSYKLIFCSVGSQGTNEKLFF
35599Homo sapiens (human)CVVSWFSDGQKLLFCSVGSQGTNEKLFF
35600Homo sapiens (human)VSESISGRKLIFCSVGSQGTNEKLFF
35601Homo sapiens (human)CAESTGKLIFCSVGTGGTNEKLFF
35602Homo sapiens (human)CATWGFCSVGTGGTNEKLFF
35603Homo sapiens (human)WTEDQRGKLMFCSVRDRVGNTIYF
35604Homo sapiens (human)CILTGGGNKLTFCSVSPVDYYTQYF
35605Homo sapiens (human)CSESNKDGNYQLIWSSSADLRTRWLLIKPSL
35763Homo sapiens (human)CAVVGTGNQFYFCAISDDRGPYEQYF
35764Homo sapiens (human)CAELGYQKVTFCANSQSPGGTQFF
35765Homo sapiens (human)CAELSDKIIFCARSQSPGGTQYF
35766Homo sapiens (human)CAEDRTGANNLFFCASADGAKIYEQYF
35767Homo sapiens (human)CVVSEGKLIFCASELWTGHNEQFF
35768Homo sapiens (human)CAEPNNAGNMLTFCASKTGTGNEKLFF
35769Homo sapiens (human)CVVNRDSSYKLIFCASNLGQILPGEQYF
35770Homo sapiens (human)WGGNWDGSYKLIFCASNLGQILPGEQYF
35771Homo sapiens (human)CAELDGQKLLFCASQNGTVNTGELFF
35772Homo sapiens (human)CAEVDAHTFLFCASQNGTVNTGELFF
35773Homo sapiens (human)CAENLYSTLTFCASSATGGDEQFF
35774Homo sapiens (human)CAMSGSNDYKLSFCASSDGQVATNEKLFF
35775Homo sapiens (human)CVVNTPNDYKLSFCASSEAGTSYYNEQFF
35776Homo sapiens (human)CVVNTPNDYKLSFCASSEAGLATTMSSSS
36568Homo sapiens (human)CGTEYPNDYKLSFAIMIGTEAF
36573Homo sapiens (human)CGTEYPNDYKLSFASSLGGNNEQF
36574Homo sapiens (human)CGTEYPNDYKLSFASSLPGTVQETQY
36575Homo sapiens (human)CGTEYPNDYKLSFASSQGQGISYEQY
36577Homo sapiens (human)CGTEYPNDYKLSFASSSTGGGEKDQPQH
36578Homo sapiens (human)CGTEYPNDYKLSFASSSGLVSNTGELF
36651Homo sapiens (human)CADSGGGADGLTFASSSPEGQPLNTGELF
36876Homo sapiens (human)CAVMDSNYQLIWSARFGRGETQY
37006Homo sapiens (human)CAASETSYDKVIFSARALPVGNTIY
37570Homo sapiens (human)CGTEINDYKLSFSAWTGTEAF
37651Homo sapiens (human)CILRDLNAGGTSYGKLTFASSEVVSTTYEQY
37845Homo sapiens (human)CAGSPSNTGKLIFASSARSSYEQY
38358Homo sapiens (human)CAVLDSNYQLIWASSSGRLTNTEAF
39493Homo sapiens (human)CAVGDNFNKFYFASSPVTGSSYEQY
39497Homo sapiens (human)CAVGDNFNKFYFASSSGLVSNTGELF
39673Homo sapiens (human)CAETHSGGSNYKLTFASSSGLVSNTGELF
39702Homo sapiens (human)CALSEAKDEGSEKLVFASSLSLHGNQPQH
39749Homo sapiens (human)CAEMEGGSYIPTFASSVTGTFGYEQY
39751Homo sapiens (human)CAEMEGGSYIPTFASSSPEGQPLNTGELF
39754Homo sapiens (human)CAEMEGGSYIPTFSVGSRGTNEKLF
40160Homo sapiens (human)CVVNGGDSSYKLIFASSEGQVSPGELF
40300Homo sapiens (human)CAWSSNAGGTSYGKLTFASSEGGFTFYNEQF
40303Homo sapiens (human)CVVNREGYSTLTFASSEGGFTFYNEQF
40304Homo sapiens (human)CVVNREGYSTLTFASSESVLGLNTEAF
41288Homo sapiens (human)CAMRSTGNQFYFASSQDPSRTYEQY
41477Homo sapiens (human)CAVPLTGGGNKLTFASSLGVAGTNTGELF
41478Homo sapiens (human)CAVPLTGGGNKLTFASSLNRGDPEAF
41479Homo sapiens (human)CAVPLTGGGNKLTFASSTRSSYEQY
41604Homo sapiens (human)CAGMNRDDKIIFSARDRVGNTIY
41723Homo sapiens (human)CAFMKQEVPGAGSYQLTFASSISGTSAYYEQY
42126Homo sapiens (human)CAVTGNNDYKLSFASSFTSGTTDTQY
43018Homo sapiens (human)CAYRSLTSGTYKYIFASSPRGGVEKTQY
43153Homo sapiens (human)CATDRAGSARQLTFSARDRTGNGYT
43593Homo sapiens (human)CAVVGTGNQFYFASSNSWGSYEQY
44586Homo sapiens (human)CAEDSNARLMFASSLGVAGTNTGELF
44587Homo sapiens (human)CAEDSNARLMFSARSRVGNTIY
44588Homo sapiens (human)CAEDSNARLMFSARDRVGNTIY
44595Homo sapiens (human)CAMKSTNAGKSTFSARDRVGNTIY
44908Homo sapiens (human)CAEDSGNLIFASSLNRGDPEAF
44909Homo sapiens (human)CAEDSGNLIFASSVAVGTGSGANVLT
45001Homo sapiens (human)CVVSDVNTDKLIFSARSRVGNTIY
45085Homo sapiens (human)CAGGNTGKLIFASSLGQGASQPQH
45774Homo sapiens (human)CAEDNNARLMFSARTGTGNSYT
45775Homo sapiens (human)CAEDNNARLMFSARVGPTGNTIY
45776Homo sapiens (human)CAEDNNARLMFSARDREFGNTIY
45777Homo sapiens (human)CAEDNNARLMFSARDRTGNGYT
45778Homo sapiens (human)CAEDNNARLMFSARDSTGNGYT
45779Homo sapiens (human)CAEDNNARLMFSASRPYSNQPQH
45780Homo sapiens (human)CAEDNNARLMFSARPQPVGNTIY
45781Homo sapiens (human)CAEDNNARLMFSARSETGNTIY
45905Homo sapiens (human)CAAILPSGGYNKLIFSARDRTGNGYT
45924Homo sapiens (human)CAESKPDKLIFASSQSPGGIQY
45925Homo sapiens (human)CAESTSGGGADGLTFASSQSPGGMQY
45926Homo sapiens (human)CAEAGANNLFFASSQSPGGTQY
45927Homo sapiens (human)CAELKEKLIFASSQSPGGTQY
45928Homo sapiens (human)CAELKEKLIFSARWGGGTDTQY
45929Homo sapiens (human)CAEYSSASKIIFASSQSPGGTQY
45930Homo sapiens (human)CAMRERMLGGGFKTIFASSQSPGGTQY
46310Homo sapiens (human)CAVGLFNFNKFYFSARDRVGNTIY
46601Homo sapiens (human)CALYNTDKLIFASSPVTGSSYEQY
46602Homo sapiens (human)CAVGLYYGNNRLAFASSPVTGSSYEQY
46603Homo sapiens (human)CTSVLCITPTSSSLASSPVTGSSYEQY
46771Homo sapiens (human)CAYMDSGTYKYIFASSPGPGWVRTDTQY
47082Homo sapiens (human)CAERASNNDMRFASSPPGLVGGELF
47083Homo sapiens (human)CAVRFNDYKLSFASSPPGLVGGELF
48188Homo sapiens (human)CALDNTGKLIFASSWNRASSYEQY
48507Homo sapiens (human)CAEDNNNDMRFASSVTGTFGYEQY
48948Homo sapiens (human)CAEKEYADGLTFASSSPEGQPLNTGELF
49000Homo sapiens (human)CAVSVGNDYKLSFASSSPGGEQF
49160Homo sapiens (human)CAVKGVTGGGNKLTFASSVAGTTDTQY
49376Homo sapiens (human)CAASGGTYKYIFASSSGRLTNTEAF
49453Homo sapiens (human)CAVSLLNDYKLSFASSTGQVTQETQY
49542Homo sapiens (human)CALSESNSGNTPLVFSAWTGTEAF
49845Homo sapiens (human)CADDNNARLMFSARTAPVGNEQF
50039Homo sapiens (human)CAVRADSGAGSYQLTFSARDRVGNTIY
50092Homo sapiens (human)CAVSENRDDKIIFSARDSTGNGYT
50347Homo sapiens (human)CAESTSGGKLIFSVGSRGTNEKLF
50375Homo sapiens (human)CAEPKGGTYKYIFSAWTGTEAF
50380Homo sapiens (human)CAESIGKLIFSVGTGGTNEKLF
50381Homo sapiens (human)CAESTGKLIFSVGTGGTNEKLF
50402Homo sapiens (human)CAEDFNARLMFSARIGVGNTIY
50884Homo sapiens (human)CAVGGLNDYKLSFSARDDSGQGFGFLETQY
50887Homo sapiens (human)CAEDSASKIIFSARDETGNGYT
51020Homo sapiens (human)CAVISNSGYALNFASTTTGNTDTQY
51401Homo sapiens (human)CAEDLQKLVFSARALPVGNTIY
51417Homo sapiens (human)CAGPPSGAGSYQLTFSARDDSGQGFGFLETQY
51418Homo sapiens (human)CAGQTNSGYALNFSARDDSGQGFGFLETQY
188222Homo sapiens (human)CAESPSSGNTPLVFCASAGPGQVYEQYV
188272Homo sapiens (human)CAVNTPNDYKLSFCASGGGGGGYYNEQFF
188423Homo sapiens (human)CVVNGRDSSYKLIFCASSAPDKAPNEQYF
188425Homo sapiens (human)CVVNGRDSSYKLIFCASSPPEQLPTEAFF
188571Homo sapiens (human)CVVNGMDSSYKLIFCASSAGRVLPGEQYF
188572Homo sapiens (human)CVVNGMDSSYKLIFCASSEGNVAPGELFF
188677Homo sapiens (human)CVVNIPNDYKLSFCASSQDGAGGLGEQYF
188748Homo sapiens (human)CAVGRSNDYKLSFCASSFSSGTTDTQYF
188777Homo sapiens (human)CVVNGADSSYKLIFCASSGGRVAPGELFF
188878Homo sapiens (human)CVVNTANDYKLSFCASSHSGQSFYNEQFF
188887Homo sapiens (human)CVVNVANDYKLSFCASSIAHVAGGNEQFF
189517Homo sapiens (human)CAVIPINDYKLSFCASSLNAGDNEQFF
189715Homo sapiens (human)CAVQAGIYNQGGKLIFCASSPGQLSNTGELFF
189716Homo sapiens (human)CGTEKANDYKLSFCASSPGQLSNTGELFF
189798Homo sapiens (human)CLVGGSYNTNAGKSTFCASSPEDYEQYF
189937Homo sapiens (human)CVVNGGDSSYKLIFCASSPQGVSPGTIYF
190106Homo sapiens (human)CAEQGNDMRFCASSQSPGGIPFF
190336Homo sapiens (human)CVVNMEGRYDMHFCASSVDTGLTGELFF
190441Homo sapiens (human)CAEDDNARLMFCSARDEVGNTIYF
190444Homo sapiens (human)CAEDNNARLMFCSARDGTGNGYTF
190446Homo sapiens (human)CAEDNNARLMFCSARIYGGGEVGNTIYF
190448Homo sapiens (human)CAEDNNARLMFCSARDRGIGNTIYF
190449Homo sapiens (human)CAEDNNARLMFCSARDRTGNGYTF
190523Homo sapiens (human)CVVNTPNDYKLSFCASSSGGGAPSGNTIYF
190649Homo sapiens (human)CAGGSSNTGKLIFCSARVGVGNTIYF
190796Homo sapiens (human)CAESTGKLIFCSVGQGGTNEKLFF
190797Homo sapiens (human)CAESTGKLIFCSVGTGGTNEKLFF
191042Homo sapiens (human)CAVALMIKAAGNKLTFCSARDQTGNGYTF
191052Homo sapiens (human)CADDNNARLMFCSARDRTGNGYTF
191116Homo sapiens (human)CALAPGGGNKLTFCSVAWVDDTQYF
191119Homo sapiens (human)CAEDTGRRALTFCSVDHAGTSENRYTF
191121Homo sapiens (human)CGTEIENDYKLSFCASSTGQLSNTGELFF
191125Homo sapiens (human)CAVWGEGDYKLSFCASSTGTVSNTGELFF
191268Homo sapiens (human)CAERTGYALNFCSVRSEGDTIYF
191322Homo sapiens (human)CAESRPGLIFCSVGTGGTNEKLFF
191323Homo sapiens (human)CAVREGGFGNVLHCCSVGTGGTNEKLFF
201267Homo sapiens (human)DNNARLKSFRHRYSE
201268Homo sapiens (human)DNNARLPPMGTPNYGY
201269Homo sapiens (human)DNNARLRDETGNGY
201270Homo sapiens (human)DNNARLRDQTGNGY
201271Homo sapiens (human)DNNARLRDRIGNGY
201272Homo sapiens (human)DNNARLRDRTGNGY
201273Homo sapiens (human)DNNARLRDRVGNGY
201274Homo sapiens (human)DNNARLRDSTGNGY
201275Homo sapiens (human)DNNARLRDSVGNGY
201276Homo sapiens (human)DNNARLRDTIGNGY
201277Homo sapiens (human)DNNARLRIGVGNTI
201278Homo sapiens (human)DNNARLRSETGNTI
201279Homo sapiens (human)DNNARLRVGVGNTI
201280Homo sapiens (human)DNNARLVGSGGTNEKL
201281Homo sapiens (human)DQSPRVRDRVGNTI
201282Homo sapiens (human)DRYSTLTTGSGDRGA
201283Homo sapiens (human)DSNARLRDREFGNTI
201284Homo sapiens (human)DSNARLRGSVGNTI
201285Homo sapiens (human)DVNARLRDRVGNGY
201288Homo sapiens (human)GGADGLSQSPGGIQ
201333Homo sapiens (human)IHNQAGTALSPPAVSYEQ
201334Homo sapiens (human)ITGGTYKYVEGLTYNEQ
201336Homo sapiens (human)NGADSSYKLTDPRLLPGEQ
201337Homo sapiens (human)NGEDSSYKLSGGQVAPSEQ
201338Homo sapiens (human)NGGDSSYKLTSGQISPSAI
201339Homo sapiens (human)NGGFKTVEDSIAGFTDTQ
201340Homo sapiens (human)NGKDSSYKLSPPGLAPNEQ
201341Homo sapiens (human)NGKDSSYKLSSLEVSPSEQ
201342Homo sapiens (human)NGMDSSYKLSEGAVAPGEQ
201343Homo sapiens (human)NGMDSSYKLSEGQVWPGEL
201344Homo sapiens (human)NGMDSSYKLTAGGTLPGEQ
201345Homo sapiens (human)NGMDSSYKLTSGTVAPGEQ
201346Homo sapiens (human)NGRDSSYKLSDGAVAPNEQ
201347Homo sapiens (human)NGRDSSYKLSGGRVAPGEL
201348Homo sapiens (human)NGRDSSYKLSSGSVAPGEL
201349Homo sapiens (human)NGRDSSYKLSVGEILPGEQ
201350Homo sapiens (human)NIPNDYKLSQDGAGGLGEQ
201356Homo sapiens (human)PNNAGNMLKTGTGNEKL
201359Homo sapiens (human)SGDRDDKIRDEVSGSWNEQ
201360Homo sapiens (human)SGGGADGLSEWTGYQPQ
201361Homo sapiens (human)SGGSQGNLFQEASYGY
201362Homo sapiens (human)SIGKLVGSGGTNEKL
201363Homo sapiens (human)SIGKLVGEGGTNEKL
201364Homo sapiens (human)SMDGYALTPDVNTEA
201365Homo sapiens (human)SPPSSASKISQSPGGTQ
201366Homo sapiens (human)SRETALSQSPGGTQ
201367Homo sapiens (human)SSSVGYVGQGGTNEKL
201368Homo sapiens (human)STGKLVGTGGTNEKL
201369Homo sapiens (human)STGKLVGYGGTNEKL
201370Homo sapiens (human)SVGKLVGTGGTNEKL
201371Homo sapiens (human)TLGNTGKLTPGQLMETQ
201372Homo sapiens (human)TSSASKIWDREVMGGNTI
204857Homo sapiens (human)CAEDNNARLMFSARDGTGNGYT
204985Homo sapiens (human)CAVSTGKLIFSVGTGGTNEKLF
205062Homo sapiens (human)CAEWGTTGFQKLVFSVEASGRTYNEQF
205227Homo sapiens (human)CAVDDGDNAGNMLTFASSGYNEQF
205637Homo sapiens (human)CALYNTDKLIFASSPTSGSVYEQY

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31324690Sunil Kumar Saini; Tripti Tamhane; Raghavendra Anjanappa; Ankur Saikia; Sofie Ramskov; Marco Donia; Inge Marie Svane; Søren Nyboe Jakobsen; Maria Garcia-Alai; Martin Zacharias; Rob Meijers; Sebastian Springer; Sine Reker HadrupSci Immunol2019Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells.
31502632Alphonsus H C Ng; Songming Peng; Alexander M Xu; Won Jun Noh; Katherine Guo; Michael T Bethune; William Chour; Jongchan Choi; Sung Yang; David Baltimore; James R HeathLab Chip2019MATE-Seq: microfluidic antigen-TCR engagement sequencing.
31568490Benjamin Faist; Fabian Schlott; Christian Stemberger; Kevin M Dennehy; Angela Krackhardt; Mareike Verbeek; Götz U Grigoleit; Matthias Schiemann; Dieter Hoffmann; Andrea Dick; Klaus Martin; Martin Hildebrandt; Dirk H Busch; Michael NeuenhahnPLoS One2019Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy.
31578295Barbara Serafini; Barbara Rosicarelli; Caterina Veroni; Gina Adriana Mazzola; Francesca AloisiJ Virol2019Epstein-Barr Virus-Specific CD8 T Cells Selectively Infiltrate the Brain in Multiple Sclerosis and Interact Locally with Virus-Infected Cells: Clue for a Virus-Driven Immunopathological Mechanism.
31765434Larisa Kamga; Anna Gil; Inyoung Song; Robin Brody; Dario Ghersi; Nuray Aslan; Lawrence J Stern; Liisa K Selin; Katherine LuzuriagaPLoS Pathog2019CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
31442594Pooja Khandelwal; Vijaya Chaturvedi; Erika Owsley; Adam Lane; Daria Heyenbruch; Carolyn M Lutzko; Thomas Leemhuis; Michael S Grimley; Adam S Nelson; Stella M Davies; Michael B Jordan; Rebecca A MarshBiol Blood Marrow Transplant2020CD38<sup>bright</sup>CD8<sup>+</sup> T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells.
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32158568Ingerid Weum Abrahamsen; Bjørn Christer Grønvold; Else Marit Inderberg; Nadia Mensali; Jonas Mattsson; Tobias Gedde-DahlCase Reports Immunol2020Posttransplantation Lymphoproliferative Disease Treated by Retransplantation.
31736946David M Burns; Gordon B Ryan; Caroline M Harvey; Eszter Nagy; Simon Hughes; Paul G Murray; Nigel H Russell; Christopher P Fox; Heather M LongFront Immunol2019Non-uniform Expansion of Epstein-Barr Virus-Specific T-Cells Following Donor Lymphocyte Infusion for Post-transplant Lymphoproliferative Disease.
33853928Sunil Kumar Saini; Ditte Stampe Hersby; Tripti Tamhane; Helle Rus Povlsen; Susana Patricia Amaya Hernandez; Morten Nielsen; Anne Ortved Gang; Sine Reker HadrupSci Immunol2021SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8<sup>+</sup> T cell activation in COVID-19 patients.
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36619639David Langan; Ruipeng Wang; Keshanti Tidwell; Selome Mitiku; Alison Farrell; Catrina Johnson; Adam Parks; Lauren Suarez; Shweta Jain; Sojung Kim; Kristi Jones; Mathias Oelke; Jerome ZeldisFront Med (Lausanne)2022AIM™ platform: A new immunotherapy approach for viral diseases.
36923729Fransenio Clark; Anna Gil; Ishwor Thapa; Nuray Aslan; Dario Ghersi; Liisa K SelinFront Immunol2022Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old.
36121440W Huisman; M C J Roex; L Hageman; E A S Koster; S A J Veld; C Hoogstraten; P van Balen; H M van Egmond; C A M van Bergen; H Einsele; L Germeroth; D Amsen; J H F Falkenburg; I JedemaBlood Adv2023Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing.
32313721Julie Charles; Laurence Chaperot; Dalil Hannani; Juliana Bruder Costa; Isabelle Templier; Sabiha Trabelsi; Hugo Gil; Anaick Moisan; Virginie Persoons; Harald Hegelhofer; Edith Schir; Jean-Louis Quesada; Christophe Mendoza; Caroline Aspord; Olivier Manches; Pierre G Coulie; Amir Khammari; Brigitte Dreno; Marie-Thérèse Leccia; Joel PlumasOncoimmunology2020An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial.
37586765Siri Amanda Tvingsholm; Marcus Svensson Frej; Vibeke Mindahl Rafa; Ulla Kring Hansen; Maria Ormhøj; Alexander Tyron; Agnete W P Jensen; Mohammad Kadivar; Amalie Kai Bentzen; Kamilla K Munk; Gitte N Aasbjerg; Jeppe S H Ternander; Christina Heeke; Tripti Tamhane; Christian Schmess; Samuel A Funt; Julie Westerlin Kjeldsen; Anders Handrup Kverneland; Özcan Met; Arianna Draghi; Søren Nyboe Jakobsen; Marco Donia; Inge Marie Svane; Sine Reker HadrupJ Immunother Cancer2023TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy.
37280206Julien Schmidt; Johanna Chiffelle; Marta A S Perez; Morgane Magnin; Sara Bobisse; Marion Arnaud; Raphael Genolet; Julien Cesbron; David Barras; Blanca Navarro Rodrigo; Fabrizio Benedetti; Alexandra Michel; Lise Queiroz; Petra Baumgaertner; Philippe Guillaume; Michael Hebeisen; Olivier Michielin; Tu Nguyen-Ngoc; Florian Huber; Melita Irving; Stéphanie Tissot-Renaud; Brian J Stevenson; Sylvie Rusakiewicz; Denarda Dangaj Laniti; Michal Bassani-Sternberg; Nathalie Rufer; David Gfeller; Lana E Kandalaft; Daniel E Speiser; Vincent Zoete; George Coukos; Alexandre HarariNat Commun2023Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
35401538Wesley Huisman; Lois Hageman; Didier A T Leboux; Alexandra Khmelevskaya; Grigory A Efimov; Marthe C J Roex; Derk Amsen; J H Frederik Falkenburg; Inge JedemaFront Immunol2022Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals.
37751288Daphne M Hullegie-Peelen; Hector Tejeda Mora; Dennis A Hesselink; Eric Mj Bindels; Thierry Pp van den Bosch; Marian C Clahsen-van Groningen; Marjolein Dieterich; Sebastiaan Heidt; Robert C Minnee; Georges Mgm Verjans; Martin J Hoogduijn; Carla C BaanJCI Insight2023Virus-specific TRM cells of both donor and recipient origin reside in human kidney transplants.
38053994Barbara Couturaud; Bastien Doix; Laura Carretero-Iglesia; Mathilde Allard; Sylvain Pradervand; Michael Hebeisen; Nathalie RuferFront Immunol2023Overall avidity declines in TCR repertoires during latent CMV but not EBV infection.
31624377Marthe C J Roex; Peter van Balen; Lothar Germeroth; Lois Hageman; Esther van Egmond; Sabrina A J Veld; Conny Hoogstraten; Ellis van Liempt; Jaap J Zwaginga; Liesbeth C de Wreede; Pauline Meij; Ann C T M Vossen; Sophia Danhof; Hermann Einsele; M Ron Schaafsma; Hendrik Veelken; Constantijn J M Halkes; Inge Jedema; J H Frederik FalkenburgLeukemia2020Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation-a phase I/II study.
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25875651Even Walseng; Sébastien Wälchli; Lars-Egil Fallang; Weiwen Yang; Anette Vefferstad; Ali Areffard; Johanna OlweusPLoS One2015Soluble T-cell receptors produced in human cells for targeted delivery.
26451296Mathieu F Chevalier; Sara Bobisse; Carla Costa-Nunes; Valérie Cesson; Patrice Jichlinski; Daniel E Speiser; Alexandre Harari; George Coukos; Pedro Romero; Denise Nardelli-Haefliger; Camilla Jandus; Laurent DerréOncoimmunology2015High-throughput monitoring of human tumor-specific T-cell responses with large peptide pools.
37133356Helle Rus Povlsen; Amalie Kai Bentzen; Mohammad Kadivar; Leon Eyrich Jessen; Sine Reker Hadrup; Morten NielsenElife2023Improved T cell receptor antigen pairing through data-driven filtering of sequencing information from single cells.

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